Browsing 2021 by Issue Date

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  • Topical formulations containing aptamer-functionalized nanocapsules loaded with 5-fluorouracil - An innovative concept for the skin cancer therapy 
    Rață, Delia-Mihaela; Cadinoiu, Anca-Niculina; Atanase, Leonard-Ionuț; Popa, Ionel-Marcel; Mihai, Cosmin-Teodor; Solcan, Carmen; Ochiuz, Lăcrămioara; Vochița, Gabriela (Elsevier B.V., 2020-10-08)
    New topical gel formulations based on sodium alginate and hyaluronic acid containing AS1411 aptamer-functionalized polymeric nanocapsules loaded with an antitumoral drug (5-Fluorouracil) were designed as an innovative approach ...
  • In-depth assessment of new Ti-based biocompatible materials 
    Spătaru, Mihaela-Claudia; Butnaru, Maria; Sandu, Andrei-Victor; Vulpe, Vasile; Vlad, Maria-Daniela; Bălțatu, Mădălina-Simona; Geantă, Victor; Voiculescu, Ionelia; Vizureanu, Petrică; Solcan, Carmen (Elsevier, 2020-10-23)
    The objective of the research is to obtain Ti20MoxSi (where x = 0, 0.5, 0.75, 1.0 wt %) alloys using the vacuum arc remelting (VAR) methods and to consider the effects of Mo and Si on physical-chemical, biological and ...
  • New Ti-Mo-Si materials for bone prosthesis applications 
    Vereștiuc, Liliana; Spătaru, Mihaela-Claudia; Bălțatu, Mădălina-Simona; Butnaru, Maria; Solcan, Carmen; Sandu, Andrei-Victor; Voiculescu, Ionelia; Geantă, Victor; Vizureanu, Petrică (Elsevier, 2020-11-07)
    Several newly obtained titanium alloys were characterized in order to evaluate the biocompatibility and their possible application as implants. For improvement of the performances of the TiMo alloys compared to other alloys, ...
  • Development and characterisation of microporous biomimetic scaffolds loaded with magnetic nanoparticles as bone repairing material 
    Cojocaru, Florina-Daniela; Balan, Vera; Tanase, Constantin-Edi; Popa, Ionel-Marcel; Butnaru, Maria; Bredețean, Ovidiu; Mareș, Mihai; Năstasă, Valentin; Pașca, Aurelian-Sorin; Vereștiuc, Liliana (Elsevier Ltd and Techna Group S.r.l., 2020-11-30)
    Fine-tuning of the scaffolds structural features for bone tissue engineering can be an efficient approach to regulate the specific response of the osteoblasts. Here, we loaded magnetic nanoparticles aka superparamagnetic iron ...
  • Imination of chitosan nanofibers in a heterogeneous system. Synthesis optimization and impact on fiber morphology 
    Anisiei, Alexandru; Bostănaru, Andra-Cristina; Mareș, Mihai; Marin, Luminița (2021)
    The paper aimed to prepare imino-chitosan fibers by the imination reaction in a heterogenous system, targeting the improvement of anti-pathogenic activity. To this end, porous neat chitosan fibers were prepared by ...
  • Experimental Induction of Type 2 Diabetes Mellitus and the Efficiency of Bariatric Surgery in its Reversal in Rats 
    Hrițcu, Luminița-Diana; Borcea, Denis-Gabriel; Anton, Emil; Moroșan, Șerban; Pașca, Aurelian-Sorin; Trincă, Lucia-Carmen; Spătaru, Mihaela-Claudia; Petrariu, Florin; Burtan, Liviu-Cătălin; Ciobîcă, Alin-Stelian; Curpan, Alexandrina; Timofte, Daniel (Romanian Society of Endocrinology, 2021)
    Following recent years, there is an increased body of literature on the connections that might exist between type 2 diabetes mellitus and the efficiency of bariatric surgery in its reversal compared to other medical ...
  • Long Term Evaluation of Biodegradation and Biocompatibility In-Vivo the Mg-0.5Ca-xZr Alloys in Rats 
    Șindilar, Eusebiu-Viorel; Munteanu, Corneliu; Pașca, Aurelian-Sorin; Mihai, Iuliana; Henea, Mădălina-Elena; Istrate, Bogdan (MDPI, 2021-01-11)
    Biodegradable alloys in Mg have the advantages of traditional metallic materials and those of biodegradable polymers with superior strength, lower density and ideal rigidity for fixing bone fractures. The biocompatibility ...
  • Parasitism with Acanthocephalus ranae in frogs (Pelophylax ridibundus Pallas 1771), from North-east Romania 
    Iacob, Olimpia (Sciendo, 2021-02-10)
    The present study was carried out on 10 frogs, Pelophylax ridibundus (Pallas, 1771), captured near the river Bahlui, Iasi, between April and May, 2019, for the study of digestive helminths and their effect on the digestive ...
  • Ultrasound and endoscopic findings in dogs with lymphangiectasia 
    Mălăncuș, Răzvan-Nicolae (Universidade Federal de Minas Gerais, Escola de Veterinária, 2021-02-12)
    Lymphangiectasia is a heterogenous inflammatory bowel disease characterized by lymphatic vessel dilation, chronic diarrhea and protein loss such as serum albumin and globulin. The most common cause of lymphangiectasia is ...
  • Mycosands: Fungal diversity and abundance in beach sand and recreational waters - Relevance to human health 
    Brandão, J.; Gangneux, Jean-Pierre; Arikan Akdagli, S.; Barac, A.; Bostănaru, Andra-Cristina; Brito, S.; Bull, M.; Çerikçioğlu, N.; Chapman, B.; Efstratiou, M.A.; Ergin, Ç.; Frenkel, M.; Gitto, A.; Gonçalves, C.I.; Guégan, H.; Gunde Cimerman, N.; Güran, M.; Irinyi, L.; Jonikaitė, E.; Kataržytė, M.; Klingspor, L.; Mareș, Mihai; Meijer, W.G.; Melchers, W.J.G.; Meletiadis, J.; Meyer, W.; Năstasă, Valentin; Novak Babič, M.; Ogunc, D.; Ozhak, B.; Prigitano, A.; Ranque, S.; Rusu, Oana-Raluca; Sabino, R.; Sampaio, A.; Silva, S.; Stephens, J.H.; Tehupeiory Kooreman, M.T.; Tortorano, A.M.; Velegraki, A.; Veríssimo, C.; Wunderlich, G.C.; Segal, E. (Elsevier B.V., 2021-03-26)
    The goal ofmost studies published on sand contaminants is to gather and discuss knowledge to avoid faecal contamination of water by run-offs and tide-retractions. Other life forms in the sand, however, are seldom studied but ...
  • The virome of Rhipicephalus, Dermacentor and Haemaphysalis ticks from Eastern Romania includes novel viruses with potential relevance for public health 
    Brătuleanu Baisan, Bianca-Elena; Temmam, Sarah; Chrétien, Delphine; Regnault, Béatrice; Pérot, Philippe; Bouchier, Christiane; Bigot, Thomas; Savuța, Gheorghe; Eloit, Marc (John Wiley & Sons, 2021-04-11)
    Ticks are involved in the transmission of various pathogens and several tick-borne diseases cause significant problems for the health of humans and livestock. The composition of viral communities in ticks and their ...
  • Kerion Celsi durch Microsporum canis 
    Chiriac, Anca; Bârsan, Cristina; Mareș, Mihai; Wollina, Uwe (Springer, 2021-04-21)
    Tinea capitis is seen world-wide among children up to 12 years. The most severe type is Kerion Celsi with painful abscesses and lymphadenopathy. We report on an 11-year-old boy with Kerion Celsi, who was initially treated ...
  • Optimized synthesis of new N-mustards based on 2-mercaptobenzoxazole derivatives with antitumor activity 
    Cheptea, Corina; Sunel, Valeriu; Moroșanu, Ana-Cezarina; Dimitriu, Dan-Gheorghe; Dulcescu Oprea, Mihaela-Maria; Angheluță, Mihai-Daniel; Miron, Mihaela; Nechifor, Cristina-Delia; Dorohoi, Dana-Ortansa; Mălăncuș, Răzvan-Nicolae (MDPI, 2021-04-26)
    New di-( -chloroethyl)-amides of some acids derived from 2-mercaptobenzoxazole were prepared by reaction of the corresponding pivalic mixed anhydrides with di-( -chloroethyl)-amine. A study regarding the optimization of ...
  • Nanomaterials and essential oils as candidates for developing novel treatment options for bovine mastitis 
    Neculai Văleanu, Andra-Sabina; Ariton, Adina-Mirela; Mădescu, Bianca-Maria; Rîmbu, Cristina-Mihaela; Creangă, Șteofil (MDPI, 2021-05-31)
    Nanomaterials have been used for diagnosis and therapy in the human medical field, while their application in veterinary medicine and animal production is still relatively new. Nanotechnology, however, is a rapidly growing ...
  • Short-term heart rate variability in healthy dogs and dogs in various stages of degenerative mitral valve disease evaluated before pharmacotherapy 
    Baisan, Radu-Andrei; Vulpe, Vasile; Ohad, D.G. (Elsevier Ltd, 2021-06-05)
    Mitral valve disease (MVD) progression is associated with autonomic nervous system (ANS) imbalance. This study hypothesized that sympathetic and parasympathetic tones would be altered with MVD progression. ANS activity ...
  • Predictive value of comorbid conditions for COVID-19 mortality 
    Marincu, Iosif; Bratosin, Felix; Vidican, Iulia; Bostănaru, Andra-Cristina; Frent, Ștefan; Cerbu, Bianca; Turaiche, Mirela; Tîrnea, Livius; Timircan, Mădălina (MDPI, 2021-06-16)
    In this paper, we aim at understanding the broad spectrum of factors influencing the survival of infected patients and the correlations between these factors to create a predictive probabilistic score for surviving the ...
  • Pegylation of phenothiazine - A synthetic route towards potent anticancer drugs 
    Cibotaru, Sandu; Năstasă, Valentin; Sandu, Andreea-Isabela; Bostănaru, Andra-Cristina; Mareș, Mihai; Marin, Luminița (Elsevier B.V. on behalf of Cairo University, 2021-07-09)
    Introduction: Cancer is a big challenge of the 21 century, whose defeat requires efficient antitumor drugs. Objectives: The paper aims to investigate the synergistic effect of two structural building blocks, phenothiazine and ...
  • Antibiotic Susceptibility Profile of Pseudomonas aeruginosa Canine Isolates from a Multicentric Study in Romania 
    Dégi, János; Ciocan Moțco, Oana-Alexandra; Dégi, Diana-Maria; Suici, Tiana; Mareș, Mihai; Imre, Kálmán; Cristina, Romeo-Teodor (MDPI, 2021-07-12)
    Treating infections caused by Pseudomonas aeruginosa is increasingly difficult due to high antibiotic resistance, materialized through the presence of multiple resistance strains, as well as due to rapid development of ...
  • In Vivo Evaluation of Biocompatibility of Three Biomaterials Used in Endodontics for Prosthetic Purposes in Complex Rehabilitation Treatment 
    Aminov, Liana; Șindilar, Eusebiu-Viorel; Pașca, Aurelian-Sorin; Antohi, Cristina; Decolli, Yllka; Stamatin, Ovidiu; Costin, Lupu-Iulian; Bulancea, Bogdan-Petru; Francu, Laurian; Mihălaș, Eugen; Checheriță, Laura-Elisabeta (MDPI, 2021-07-15)
    The ideal biomaterial used in endodontics in the process of sealing the radicular canals should possess a group of qualities for a predictable outcome: biocompatibility, initiation of ontogenesis and cementogenesis, ease ...
  • Cortisol and Oxytocin Could Predict Covert Aggression in Some Psychotic Patients 
    Popescu, Elena-Rodica; Semeniuc, Suzana; Hrițcu, Luminița-Diana; Horhogea, Cristina-Elena; Spătaru, Mihaela-Claudia; Truș, Constantin; Dobrin, Romeo-Petru; Chiriță, Vasile; Chiriță, Roxana (MDPI, 2021-07-27)
    Background: The covert or indirect type of aggression has a risk of converting in violent acts and, considering that, it is very important to identify it in order to apply effective preventive measures. In cases of psychotic ...