Canine granulomatous meningoencephalitis: a case report and review of the literature

Abstract

Canine granulomatous meningoencephalomyelitis (GME) is a subtype of a large group of idiopathic central nervous system diseases with a relatively high incidence (up to 25%) among dogs with central nervous system affection (Tipold, 1995). Neurological presentation of GME can vary from focal to multifocal, or ocular form. Histologically, GME is characterized by focal, disseminated or perivascular mononuclear cells spreading in the white matter and meninges (Coates and Jeffery, 2014). The aim of the current case report is to describe the pathological findings and to discuss the diagnostic features of this disease. Therefore, we should further emphasize the importance of this disease in current veterinary practice.