The influence of a probiotic product with Bacillus subtilis and Pediococcus acidilactici on some hematological and clinical parameters of healthy dogs

Abstract

The study was conducted at the University of Veterinary Medicine in Cluj-Napoca (Romania) in the animal physiology department, between May 2018 and June 2019. The aim of the study was to assess the influence of a probiotic product with Bacillus subtilis and Pediococcus acidilactici on healthy dogs. The probiotic was administered orally once a day to six healthy adult dogs from 1 year to 7 years old for a period of 30 days. The dogs entering the study were submitted to a general clinical examination. At day 1 and day 31/36 of the study, blood samples was collected and haematological parameters were evaluated. The objectives of the research were multiple. First of all, we observed whether the probiotic influenced the general health of the dogs and changes in clinical parameters. Then, the dynamics of the haematological parameters was identified. The in vivo study showed the safety of the probiotic product on healthy dogs and the minimal impact on hematologic parameters. In fact, no adverse reactions were observed.