Antimicrobial activity of an active biological bioproduct obtained from grape seeds

Abstract

At the Research Station for Viticulture and Enology Iasi, a polymeric condensed proanthocyanidins was obtained from Fetească neagră grape seeds, through a phase preparation, which under determined conditions with hydrogen peroxide, led to the production of a water-soluble bio product with antibacterial, antifungal and antioxidant properties. Evaluation of the antimicrobial activity of the bio product was performed by determining minimum inhibitory concentration (MIC) and minimal bactericidal concentration (CMB) against Staphylococcus aureus and Escherichia coli. From the analysis of the obtained data it was found that the bio product reacted differently from the tested species, being more active against Staphylococcus aureus (G +). The determined MIC was 1.5 mg/mL and the CMB 2.0 mg / mL. In the case of the Escherichia coli (G-) test, the MIC and CMB values were equal but increased to 3.0 mg/mL.