Clinical and biochemical studies on contagious caprine pleuropneumonia with special reference to lipoproteins profile and fibrinogen levels

Abstract

Contagious caprine pleuropneumonia (CCPP) is a worldwide disease that lead to great economic losses. The goal of this investigation was to investigate the hematological picture, lipid profile and fibrinogen levels in goats with CCPP. A total of 355 goats were selected for this study. CapriLAT Latex Agglutination test was used to detect antibodies rapidly against Mycoplasam capricolum subspecies capripneumoniae (Mccp) from serum samples ((N=355). Then paired blood samples were collected from 65 Mycoplasma capricolum subsp. capripneumoniae (Mccp)-infected goats (positive cases), together with 20 healthy controls. Lipid profile, blood hematology picture and some biochemical blood values were determined. The examined hematological parameters revealed a significant increase in total leucocytic counts, neutrophil and monocytes with a significant decrease in PCV value, hemoglobin content, RBC count in the goats with Mccp compared with the control group. Biochemical parameters examination revealed increased in the diseased goats, except high-density lipoprotein cholesterol (HDL-c), and total cholesterol that found significantly decreased than control group. Fibrinogen value was consider higher in the diseased goats when compared to the control ones. This study will open avenue on the possible pathophysiological role of hematological parameters, lipid profile and fibrinogen in goats that affected with CCPP.