Bioisosters' impact on wine conditioning

Abstract

Bioisosters are compounds with different substituents and with similar biological, physical or chemical properties. Pyridazine derivatives bioisosters are compounds with an intense biological activity, being used as anticancer, antituberculosis, antihypertensive, antifungal or antimicrobial agents. Several studies have tested the effect of some cyclic compounds with nitrogen in wine conditioning because stabilisation treatments against metal case are frequent operations used in winemaking production. The present paper aims to improuve the oenological products array used in wine conditioning, using pyridazine derivatives bioisosters, capable to expel the excess of metals, by complexing reactions. The impact of the tested compounds was studied on wines obtained from Fetească regală grape variety. The analysis method used was atomic absorption spectrometry.