Biochemical and metabolic responses of rabbits (Oryctolagus cuniculus) to moderate and chronic stress

Abstract

The aim of this study was to evaluate the effects of moderate and chronic stress on the biochemical and metabolic responses of rabbits (Oryctolagus cuniculus). The experiment involved three groups of animals: the control group (L1), the group exposed to moderate stress (L2), and the group exposed to chronic stress (L3), each consisting of 20 individuals. The analyzed parameters included glucose, cholesterol, total proteins, albumin, and plasma cortisol. The rabbits were subjected to different stress induction protocols for two and four weeks, respectively, and blood samples were collected for biochemical analysis. The results revealed that stress exposure led to significant increases in plasma cortisol and glucose levels, particularly in the chronic stress group. Alterations in albumin and cholesterol levels were also observed, suggesting a disruption of metabolic homeostasis. The differences among groups were statistically confirmed (p < 0.05). This study highlights the profound impact of chronic stress on the metabolic responses of rabbits, emphasizing the necessity of managing stressors in companion animals and experimental settings. These findings contribute to a better understanding of the physiological mechanisms involved in stress responses and offer insights for improving animal welfare.