Study on the hematological alterations in hemorrhagic shock

Abstract

Hemorrhagic shock, characterized by significant blood loss, triggers a cascade of hematological and physiological responses that aim to maintain tissue perfusion and oxygen delivery. The study was performed on a total number of 15 pets, canine and feline, provide an in-depth analysis of the hematological changes associated with hemorrhagic shock, focusing on the alterations in blood cell counts, coagulation pathways, and oxygen-carrying capacity. Key aspects include erythrocyte depletion, platelet dysfunction, coagulopathies, and the role of biomarkers like hemoglobin, hematocrit, and lactate levels in diagnosing and assessing the severity of shock. The article also explores compensatory mechanisms, such as increased erythropoiesis and the influence of inflammatory responses, revealing a reticulocytic reaction in 14 patients while increased granulocytes levels were found in 7 pets. A better understanding of these hematological parameters can aid in early diagnosis, effective resuscitation strategies, and improved patient outcomes in hemorrhagic shock management.