Pyridazine izomers with biological activity

Abstract

Isomers are chemical compounds different from each other, with individualized physical and chemical properties. Dimethyl 2-butenoate is a symmetricall substitued alkene, with two isomeric structures: cis (dimethyl maleate) and trans (dimethyl maleate). By the addition reaction of dimethyl 2-butenoate to pyridazine salts, pyridazine isomeric derivatives are obtained. The existence of isomeric structures was proven spectrally. The biological effect of pyridazine isomers was analyzed, through tests, carried out in special chambers with controlled temperature. The results proveded the influence of the tested compounds in the germination process of wheat seeds, in the development and weight of the fresh seedlings.