Abstract:
Composite membranes based on a polymer mixture solution of quaternized polysulfone (PSFQ), cellulose acetate phthalate (CAP), and polyvinylidene fluoride (PVDF) for biomedical applications were successfully obtained through the electrospinning technique. To ensure the polysulfone membranes’ functionality in targeted applications, the selection of electrospinning conditions was essential. Moreover, understanding the geometric characteristics and morphology of fibrous membranes is crucial in designing them to meet the performance standards necessary for future biomedical applications. Thus, the viscosity of the solutions used in the electrospinning process was determined, and the morphology of the electrospun membranes was examined using scanning electron microscopy (SEM). Investigations on the surfaces of electrospun membranes based on water vapor sorption data have demonstrated that their surface properties dictate their biological ability more than their specific surfaces. Furthermore, in order to understand the different macromolecular rearrangements of membrane structures caused by physical interactions between the polymeric chains as well as by the orientation of functional groups during the electrospinning process, Fourier transform infrared (FTIR) spectroscopy was used. The applicability of composite membranes in the biomedical field was established by bacterial adhesion testing on the surface of electrospun membranes using Escherichia coli and Staphylococcus aureus microorganisms. The biological experiments conducted establish a foundation for future applications of these membranes and validate their effectiveness in specific fields.
