Abstract:
The use of etomidate for short periods of anaesthesia
(e.g. biopsy, skin suture, radiography) was related both to its short duration
of action and the absence of significant side-effects. It was rapidly
metabolized by liver in inactive metabolites, and its pharmaco-kinetics
characteristics recommended it for continuous perfusion or intravenously.
In dog, alfentanyl was used to diminish the induction dose of intravenous
anaesthesia, although it may be the cause of a few minutes apnea. The aim
of this study was to monitor the course of anaesthesia, using a combination
of etomidate and alfentanyl.