Influence of some fractions isolated from red wine on oxygen cellular consumption

Abstract

In this study, we carried out the analyse of some polyphenolic fractions obtained from a sample of red wine by solid-liquid repartition. The wine selected sample was obtained by mixing noble wine varieties, with the purpose of realising a great concentration of phenolic compounds. The fractions obtained from this special sample were firstly chemically analysed (total quantity of polyphenols, total quantity of anthocyans, Folin-Ciocâlteu index and permanganate index), and then were correlated with their specific effects on the intensity of oxygen respiratory consumption of the batracian muscle and hepatic cells, carried out by the Warburg micromanometrical method. Different biological effects (values of oxygen cellular consumption) were recorded, according to the type of cells, composition of fractions (polyphenol quantity) and duration of records. The obtained results evidenced a specific influence of the studied fractions on the respiratory and energetic cellular processes, indicating a series of useful pharmacological properties of some wine fractions.