The detection and quantification of mycotoxins difuranice in medicinal species

Abstract

Species (medicinal species) is a pharmaceutical form made up of mixtures of different plant organs (plant products), dried, which is used in therapy in the form of infusions, decoctions, macerates, syrups, tinctures, glycerine extracts, oil extracts, wine etc. In temperate continental area in which our country stands, saprophyte fungi live on the medicinal herbs so the medicinal species are often seen as different mycotoxins, metabolites of fungi. The highest incidence in this type of phyto is represented by mycotoxinsdifuranice (aflatoxins and sterigmatocistins), ochratoxin and patulin. The objective of this work consists in the qualitative and quantitative determination of mycotoxins in samples of medicinal species from pharmacies, freelance producers deprived of knowledge of toxicokinetics and toxicodynamics active principles of plants and herbal shops. The experiment was performed on 36 samples of vegetable and medicinal species, samples that were tested by first screening test in LUV and samples which showed fluorescence were studied further by high pressure chromatography. Most plant products from manufacturers freelancers do not correspond with the organoleptic rules and shows mycotoxins load.